Maciel Prenatal Interpreter (MPI) is a software system for identifying fetuses at risk for open neural tube defects (ONTD), Down Syndrome, trisomy 18, and Smith-Lemli-Opitz Syndrome (SLOS) using established methods.
MPI provides a total management system that allows you to do everything quickly and accurately – your way – using your ID numbers, test units and cutoffs. Ours is the system of choice of over 575 prenatal programs, in more than 35 countries, and a dozen state-run US programs for more than twenty years.
Overview
- Flexible and easy to use, with complete online help and detailed error checking
- Complete sample accessioning
- Identifies fetuses at risk for open neural tube defects (ONTD), Down Syndrome, trisomy 18, trisomy 13, and Smith-Lemli-Opitz Syndrome (SLOS) using established methods with your cutoffs
- Supports screening in first and second trimester, integrated screening, and amniotic fluid analysis at any time
- Calculates corrected multiples of the median (MoMs) for serum AFP, hCG, uE3, inhibin, ITA/h-hCG, PAPP-A, PlGF, and fluid AFP
- Adjusts for ultrasound markers: nuchal translucency (NT), DVPI, and nasal bone present/absent
- Freely add comments to samples
- Calculates twin risks, combination race code/diabetic/multiple gestation cutoffs
- Dated median tables – your past medians stay on file
- Gestational age by LMP, physical exam, ultrasound, EDD, or IVF
- Racial median tables – each demographic group can have its own table; no need to use correction factors; old tables stay on file
- Weight correction for each race code/substance; correction by log-linear or linear-reciprocal
- Issues interpretive reports with wording fully under your control, including graphs and color-coding
- Print reports to PDF or paper; save modified reports
- Offers an extensive menu of reports
- Interfaces with most Laboratory Information Systems (LIS)
- Calculates raw and regressed medians based on your patient data for each substance
- Validation procedure ensures correct operation
- Multi-level access and password protection for restricting software use
- Weight correction option; generate/check your own weight correction formula in a report
User-Configurable Parameters
- Weight correction for all serum markers
- Weight correction limits
- Daily or weekly medians
- Medians based on maternal age to the day or completed years
- Many choices of statistical parameter sets for risk calculations
- Up to four qualitative levels of AFP MoMs (low, normal, borderline, or elevated)
Sample Accessioning Features
- Patient demographics include: birth date, maternal weight, race, insulin-dependent diabetic status, smoking status, history of NTD and FDS, IVF dates
- Gestational age: you choose the calculation method to determine age
- Sample data: includes date drawn & received, maternal serum or amniotic fluid sample
- Plus: patient and physician’s name and address, family history and background, follow-up data
- Group samples into batches to facilitate multi-user workflow
Interface Features
- Data management interfaces enable test results to be entered automatically
- Interfaces can automatically correct for diluted samples
- LIMS: Laboratory Information Management System – a generic, unidirectional or bi-directional communication for downloading demographics and test requests and uploading results
Deployment options
- Store your data where it works for you – on the workstation, network share, or a database server
- Database server deployment allows simultaneous data entry from multiple workstations.